Synthesis and study of anti-inflammatory activity of some novel cyclophane amides |
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Authors: | Rajakumar Perumal Mohammed Abdul Rasheed A Iman Rabia A Chamundeeswari D |
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Affiliation: | Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai 600 025, India. perumalrajakumar@hotmail.com |
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Abstract: | Macrocyclic di- and tetra-amides with thia- and oxylinkages were synthesized and screened for in vitro anti-inflammatory activity. Cyclophane diamide 15 showed a dose-dependent activity, while the other cyclophane amides 16-20 exhibited mild activity. |
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