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Synthesis and study of anti-inflammatory activity of some novel cyclophane amides
Authors:Rajakumar Perumal  Mohammed Abdul Rasheed A  Iman Rabia A  Chamundeeswari D
Affiliation:Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai 600 025, India. perumalrajakumar@hotmail.com
Abstract:Macrocyclic di- and tetra-amides with thia- and oxylinkages were synthesized and screened for in vitro anti-inflammatory activity. Cyclophane diamide 15 showed a dose-dependent activity, while the other cyclophane amides 16-20 exhibited mild activity.
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