<Emphasis Type="Italic">CYP2E1</Emphasis> gene polymorphism and ovarian cancer risk in the Yakut population |
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| Authors: | A V Khrunin F G Ivanova A A Moiseev V A Gorbunova S A Limborska |
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| Institution: | 1.Institute of Molecular Genetics,Russian Academy of Sciences,Moscow,Russia;2.Yakut Republican Cancer Clinic,Yakutsk,Russia;3.Blokhin Russian Cancer Research Center,Russian Academy of Medical Sciences,Moscow,Russia |
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| Abstract: | The CYP2E1 gene polymorphism has been studied in Yakut women with ovarian cancer and without cancer. The two groups have been found
to substantially differ in the frequency of the CYP2E1*1D allele (with a 96-bp insertion in the promoter region of the gene): it is more frequent in healthy women (16.3 versus 7.4%,
P = 0.007). |
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