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| 人乳腺癌干细胞异种移植动物模型的制备和应用 | |
| 引用本文： | 许炜茹,林洪生,陈信义,张英. 人乳腺癌干细胞异种移植动物模型的制备和应用[J]. 中国实验动物学报, 2010, 18(5): 429-432. DOI: 10.3969/j.issn.1005-4847.2010.05.16 |
| 作者姓名： | 许炜茹 林洪生 陈信义 张英 |
| 作者单位： | 1. 中国中医科学院广安门医院肿瘤科,北京100053;北京中医药大学,北京100029 2. 中国中医科学院广安门医院肿瘤科,北京,100053 3. 北京中医药大学,北京,100029 |
| 摘 要： | 越来越多的证据显示乳腺癌干细胞是导致乳腺癌发生、发展、复发和转移的根源。因此,模拟出与人乳腺癌发病机制相似的动物模型将对乳腺癌的治疗起着至关重要的作用。本文旨在介绍乳腺癌干细胞异种移植动物模型的制备方法、应用以及近年来的研究进展。 |
| 关 键 词： | 乳腺癌 干细胞 动物 |
Establishment and Application of Animal Models of Xenotransplantation of Human Breast Cancer Stem Cells |
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| XU Wei-ru,LIN Hong-sheng,CHEN Xin-yi,ZHANG ying. Establishment and Application of Animal Models of Xenotransplantation of Human Breast Cancer Stem Cells[J]. Acta Laboratorium Animalis Scientia Sinica, 2010, 18(5): 429-432. DOI: 10.3969/j.issn.1005-4847.2010.05.16 | |
| Authors: | XU Wei-ru LIN Hong-sheng CHEN Xin-yi ZHANG ying |
| Affiliation: | 1.Oncology Department,Guang＇anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;2.Beijing University of Chinese Medicine,Beijing 100029,China) |
| Abstract: | Accumulating evidence shows that breast cancer stem cells are the origin of carcinogenesis,tumor progression,relapse and metastasis.Therefore animal models simulating similar pathogenesis of human breast cancer will play an important role in the research on treatment of breast cancer.This review aims to introduce the method,application and progress of in research on animal models of human breast cancer stem cells. |
| Keywords: | Breast cancer Stem cell Animal |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |