Severity of arthritis is predicted by antibody response to gp135 in chronic infection with caprine arthritis-encephalitis virus. |
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| Authors: | D Knowles Jr W Cheevers T McGuire T Stem and J Gorham |
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| Institution: | Animal Disease Research Unit, U.S. Department of Agriculture-Agricultural Research Service, Pullman, Washington 99164-7030. |
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| Abstract: | Antibody titers to caprine arthritis-encephalitis virus surface glycoprotein gp135 and core protein p28 in synovial fluid and serum from 35 goats infected for 3 years were compared with the histologic severity of arthritis in these animals. Anti-gp135 antibody titers in synovial fluid and serum directly reflect the severity of carpal arthritis in chronically infected goats. |
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