| 益生菌抑制致病菌作用的机制研究进展 |
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| 引用本文： | 张英春,韩雪,单毓娟,张兰威.益生菌抑制致病菌作用的机制研究进展[J].微生物学通报,2012,39(9):1306-1313. |
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| 作者姓名： | 张英春 韩雪 单毓娟 张兰威 |
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| 作者单位： | 哈尔滨工业大学食品科学与工程学院 黑龙江哈尔滨 150090 |
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| 基金项目： | 中央高校基本科研业务费专项资助项目(No. HIT.NSRIF.2012082); 国家863计划项目(No. 2007AA10Z354) |
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| 摘 要： | 致病菌引起的各种胃肠道疾病对人类健康造成危害,应用益生菌制剂防治致病菌感染,具有安全和减少耐药性等优点,为控制致病菌感染性疾病提供了新的途径。主要从益生菌与致病菌竞争黏附位点、与致病菌的共聚作用及其产生的抗菌物质三个方面综述益生菌抑制致病菌的作用机制。
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| 关 键 词： | 益生菌 致病菌 抑制 |
Recent advances in mechanism on probiotic bacteria inhibition of pathogens |
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| Zhang Ying-chun,HAN Xue,SHAN Yu-Juan and Zhang Lan-wei.Recent advances in mechanism on probiotic bacteria inhibition of pathogens[J].Microbiology,2012,39(9):1306-1313. |
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| Authors: | Zhang Ying-chun HAN Xue SHAN Yu-Juan and Zhang Lan-wei |
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| Institution: | School of Food Science and Engineering, Harbin Institute of Technology, Harbin, Heilongjiang 150090, China |
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| Abstract: | Pathogens is a major cause of gastrointestinal illness and hazardous to human health. Application of probiotics to the prevention of pathogen infection has received much attention due to safety and decreasing drugtolerance. Here we summarize the recent progress in mechanism of probiotic bacteria inhibition of pathogens including competition for adhesion sites with pathogens, coaggregation with pathogens and production of antimicrobial substances. |
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| Keywords: | probiotic bacteria pathogen inhibition |
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