Verification of immunosuppression in chicks caused by Cryptosporidium baileyi infection using Brucella abortus strain 1119-3 |
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Authors: | Jae Ku Rhee Hong Ji Yang Hyeon Cheol Kim |
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Affiliation: | Bio-Safety Research Institute, Veterinary School, Chonbuk National University, Chonju, Korea. |
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Abstract: | Humoral immune response of young chicks to Brucella abortus strain 1119-3 inoculation was monitored to verify the degree of immunosuppression caused by infection with Cryptosporidium baileyi. Young chicks (2-day-old) were orally inoculated each with 2 × 106 oocysts of C. baileyi, and then injected intramuscularly with 0.3 ml B. abortus strain 1119-3 containing 1 × 109 living organisms on day 14 postinoculation (PI). Serum samples were tested by plate agglutination test on day 17 PI onwards at an interval of 3-6 days over a period of 36 days. Infected chicks with the coccidium showed significantly lower antibody titers than those of uninfected controls (P < 0.05). These findings document that C. baileyi infection in early life stage may predispose chicks easily to other potential poultry diseases. |
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Keywords: | Cryptosporidium baileyi Brucella abortus immunosuppressive effect chick |
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