|
|||||
|
|
Cytotoxic ent-kaurane diterpenoids from Isodon sinuolata |
|
| Authors: | Fei He Wei-Lie Xiao Jian-Xin Pu Ying-Li Wu Hai-Bo Zhang Xiao-Nian Li Yong Zhao Li-Bin Yang Guo-Qiang Chen Han-Dong Sun |
| Institution: | aState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People’s Republic of China;bDepartment of Pathophysiology and Key Laboratory of Cell Differentiation and Apoptosis of Chinese Academy of Sciences, Shanghai 200025, People’s Republic of China;cGraduate University of Chinese Academy of Sciences, Beijing 100039, People’s Republic of China |
| Abstract: | Five (1–5) ent-kaurane diterpenoids and 17 other known ones, were isolated from the leaves and stems of Isodon sinuolata. Their structures were determined on the basis of spectroscopic methods including 1D and 2D NMR spectroscopic analysis. All compounds were evaluated for cytotoxicity against a small panel of cell lines. Some compounds exhibited significant cytotoxicity. |
| Keywords: | Isodon sinuolata Labiatae Diterpenoids Cytotoxicity |
| 本文献已被 ScienceDirect 等数据库收录！ | |