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As good as they get: cells in nematode vulva development and evolution
Authors:Ralf J. Sommer
Affiliation:Max-Planck Institute for Developmental Biology, Spemannstrasse 37-39, D-72076 Tübingen, Germany. ralf.sommer@tuebingen.mpg.de
Abstract:Cells are important modules of biological systems, and many evolutionary alterations involve changes in cell determination and cell proliferation. Genetic and molecular comparisons of nematode vulva development between Caenorhabditis, Pristionchus and Oscheius indicate that although the vulva is a stable organ, cell determination and proliferation change dramatically during nematode evolution.
Keywords:cell determination   cell differentiation   Hox genes   RAS signalling   lin-12/Notch   C.elegans   P. pacificus   Oscheius   evolution   development
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