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Metal–Organic Frameworks for Photodynamic Therapy: Emerging Synergistic Cancer Therapy |
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| Authors: | Yucong Song Lei Wang Zhigang Xie |
| Institution: | 1. State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 P. R. China
University of Science and Technology of China, Hefei, 230026 P. R. China;2. State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 P. R. China |
| Abstract: | Photodynamic therapy (PDT) conducted by photosensitizers producing cytotoxic reactive oxygen species (ROS) under light irradiation is widely used in cancer treatment. A great number of photoactive nanoscale metal–organic frameworks (NMOFs) have been prepared for PDT. With the development of biomedicine and nanotechnology, many synergistic cancer therapies have emerged. In this mini-review, an overview on the latest progress in the application of NMOFs in PDT is provided, with emphasis on the recent emergence of some synergistic therapies. |
| Keywords: | cancer treatment hypoxic tumors nanoscale MOFs photodynamic therapy synergistic therapy |