Abstract: | Adenylate cyclase and cyclic AMP phosphodiesterase activitieson the foliate papillae of rabbit were studied by means of histochemistry.In unfixed papillae the reaction product for adenylate cyclaseactivity was localized in the apex of taste buds, lamina proprioand connective tissue core of the papillae, but in fixed papillaeit was limited to the apex of taste buds. The reaction productfor cyclic AMP phosphodiesterase activity was limited to theapex of taste buds in unfixed and fixed papillae. Neither anacceleratory nor an inhibitory effect of sweet and bitter substanceson the adenylate cyclase and cyclic AMP phosphodiesterase activitieswas demonstrated, but NaCl prevented the formation of reactionproduct for the adenylate cyclase activity at the apex of tastebuds. |