Carbohydrate-modulated DNA photocleavage: design, synthesis, and evaluation of novel glycosyl anthraquinones |
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| Authors: | Toshima K Maeda Y Ouchi H Asai A Matsumura S |
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| Affiliation: | Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Yokohama, Japan. toshima@applc.keio.ac.jp |
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| Abstract: | Novel and artificial anthraquinone-carbohydrate hybrids were designed and synthesized, and found to effectively cleave DNA under irradiation with a long wavelength UV light and also exhibit cytotoxicity against HeLa S3 cells. |
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