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T160-phosphorylated CDK2 defines threshold for HGF-dependent proliferation in primary hepatocytes
Authors:Katharina Waldow  Xiaoyun Huang  Lorenza A D'Alessandro  Sebastian Bohl  Kathleen Börner  Dirk Grimm  Steffen Klamt  Ursula Klingmüller  Marcel Schilling
Affiliation:1. Division Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Heidelberg, Germany;2. Translational Lung Research Center (TLRC), Member of the German Center for Lung Research (DZL), Heidelberg, Germany;3. Centre for Infectious Diseases, Virology, Heidelberg University Hospital, Cluster of Excellence CellNetworks, Heidelberg, Germany;4. German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany;5. Analysis and Redesign of Biological Networks, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany
Abstract:
Keywords:G1/S transition   hepatocyte proliferation   HGF   mathematical model   threshold
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