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Serologic survey of West Nile virus in horses from Central-West,Northeast and Southeast Brazil
Authors:Jaqueline Raymondi Silva  Larissa Campos de Medeiros  Vinícius Pinho dos Reis  Juliana Helena Chávez  Thiago Demarchi Munhoz  Gustavo Puia Borges  Otavio Augusto Brioschi Soares  Carlos Henrique Coelho de Campos  Rosangela Zacarias Machado  Cristiane Divan Baldani  Maria Luana Cristiny Rodrigues Silva  Joice Lara Maia Faria  Edson Elias da Silva  Luiz Tadeu Moraes Figueiredo
Abstract:Since the emergence of West Nile virus (WNV) in North America in 1999, there have been several reports of WNV activity in Central and South American countries. To detect WNV in Brazil, we performed a serological survey of horses from different regions of Brazil using recombinant peptides from domain III of WNV. Positive samples were validated with the neutralisation test. Our results showed that of 79 ELISA-positive horses, nine expressed WNV-specific neutralising antibodies. Eight of the infected horses were from the state of Mato Grosso do Sul and one was from the state of Paraíba. Our results provide additional evidence for the emergence of WNV in Brazil and for its circulation in multiple regions of the country.
Keywords:West Nile virus  Flavivirus  Brazil
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