Metalloproteinases in the larvae of Echinococcus granulosus. |
| |
Authors: | M Marco A Nieto |
| |
Institution: | Cátedra de Inmunologia, Facultad de Quimica, Montevideo, Uruguay. |
| |
Abstract: | Proteolytic activity in hydatid cyst fluid, cyst membranes and protoscoleces of E. granulosus was analyzed by electrophoresis in gelatin-containing polyacrylamide gels, including characterization with a set of protease inhibitors. All contained metalloproteinases in the range 60-120 kDa, with neutral/alkaline pH optima. Major activity was observed in hydatid fluid and the membranes (five bands) with both exhibiting similar electrophoretic patterns. The samples prepared from protoscoleces shared only some of these bands. |
| |
Keywords: | |
|
|