N-Band polymorphism of human acrocentric chromosomes and its relevance to satellite association |
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Authors: | Isamu Hayata Mitsuo Oshimura Avery A Sandberg |
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Institution: | (1) Roswell Park Memorial Institute, 14263 Buffalo, New York, USA |
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Abstract: | Summary With the aid of Q- and N-banding techniques we investigated the relationship between the length of satellite stalks, the appearance of N-bands and the frequency of satellite association of individual acrocentric chromosomes in the cells of seven individuals, including one male with a satellited and small Y-chromosome. The appearance of N-bands seemed to be a constant and characteristic property of individual acrocentric chromosomes, independent of the status of concentration of the chromosomes at metaphase. The homolog with longer satellite stalks had larger N-bands and participated in satellite association at a higher frequency than the one with shorter stalks. It appeared that N-bands were present along the whole length of the satellite stalk, the size of which could possibly reflect the amount of rDNA present in the nucleolar organizers in human chromosomes. |
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