Characterization of adrenergic receptors on proximal tubular basolateral membranes |
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| Authors: | R E Jensen W O Berndt |
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| Institution: | University of Nebraska Medical Center, Department of Pharmacology, College of Medicine, Omaha 68105. |
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| Abstract: | Alpha adrenergic receptors are identified on basolateral plasma membranes derived from proximal tubular epithelial cells. The density of alpha 2 receptors was over two-fold greater than alpha 1 receptors. The basolateral membranes were devoid of beta receptors. These results support previous demonstrations of alpha adrenergic receptors in rat renal cortex and concur with studies which suggest a limited presence of beta receptors on rat proximal tubules. |
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