The Arabidopsis LHP1 protein colocalizes with histone H3 Lys27 trimethylation |
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| Authors: | Zhang Xiaoyu Germann Sophie Blus Bartlomiej J Khorasanizadeh Sepideh Gaudin Valerie Jacobsen Steven E |
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| Affiliation: | Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, California 90095, USA. |
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| Abstract: | Polycomb proteins are required for maintenance of silent chromatin states via histone H3 Lys27 trimethylation (H3K27me3) in animals, but homologs are not found in plant genomes. Using a DamID-chip method, we found that the Arabidopsis thaliana chromodomain-containing protein LHP1 colocalizes with H3K27me3 genome-wide. The LHP1 chromodomain also binds H3K27me3 with high affinity, suggesting that LHP1 has functions similar to those of Polycomb. |
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