A convenient and efficient protocol for oxidative aromatization of Hantzsch 1,4-dihydropyridines using benzyltriphenylphosphonium peroxymonosulfate under almost neutral reaction conditions |
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| Authors: | Adibi Hadi Hajipour Abdol Reza |
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| Institution: | Department of Medicinal Chemistry, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah 67168-67346, Islamic Republic of Iran. hadibi@kums.ac.ir |
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| Abstract: | Oxidative aromatization of 4-alkyl or aryl and heterocyclic-substituted derivatives of Hantzsch 1,4-dihydropyridines to the corresponding pyridine derivatives has been studied using benzyltriphenylphosphonium peroxymonosulfate as an oxidant in the presence of BiCl(3) under nearly neutral reaction conditions at ambient temperature. |
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