Synthesis and NMR properties of novel 5,6-dihydroborauracil derivatives |
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Authors: | Tomasz Ruman Karolina D?ugopolska Agata Jurkiewicz Wojciech Rode |
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Institution: | a Rzeszów University of Technology, Faculty of Chemistry, Department of Biochemistry and Biotechnology, 6 Powstańców Warszawy Avenue, Rzeszów 35-959, Poland b University of Warsaw, Faculty of Chemistry, Quantum Chemistry Laboratory, 1 Pasteur Street, Warsaw 02-093, Poland c Pharmaceutical Research Institute, Rydygier Street 8, Warsaw 01-793, Poland d Nencki Institute of Experimental Biology, 3 Pasteur Street, Warsaw 02-093, Poland |
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Abstract: | Novel boron compounds - 5,6-saturated borauracil derivatives (4-bromo-5,6-dihydroborauracil, 4-hydroxy-5,6-dihydroborauracil and 4-methoxy-5,6-dihydroborauracil) are presented along with other boron compounds obtained from N-vinylurea: N-substituted β-boronic amino acid - 2-{(dihydroxyborano-amino)(dihydroxyboranooxy)methyl]-amino}ethylboronic acid and substituted methoxy-borane O-(1-amino-1-N-vinylamino)methyl]dihydroxyboronate. |
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Keywords: | Borauracil Dihydroborauracil Hydroboration N-vinylurea |
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