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A new Smurf in the village. |
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| Authors: | K Arora R Warrior |
| Affiliation: | Department of Developmental and Cell Biology, University of California, Irvine 92697, USA. |
| Abstract: | TGF-beta signaling is modulated by Smurfs, E3-ubiquitin ligases that selectively target the receptors and Smad proteins for degradation. New evidence from Drosophila suggests that Smurfs regulate the amplitude and the duration of the cellular response to signaling in vivo. |
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