Adult midgut expressed sequence tags from the tsetse fly <Emphasis Type="Italic">Glossina morsitans morsitans</Emphasis>and expression analysis of putative immune response genes期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Adult midgut expressed sequence tags from the tsetse fly <Emphasis Type="Italic">Glossina morsitans morsitans</Emphasis>and expression analysis of putative immune response genes

Authors:	Email author" target="_blank">M?J?Lehane Email author S?Aksoy W?Gibson A?Kerhornou M?Berriman J?Hamilton M?B?Soares M?F?Bonaldo S?Lehane N?Hall

Institution:	(1) School of Biological Sciences, University of Wales, LL57 2UW Bangor, UK;(2) Department of Epidemiology and Public Health, Section of Vector Biology, Yale University, 06510 New Haven, CT, USA;(3) School of Biological Sciences, University of Bristol, BS8 1UG Bristol, UK;(4) The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, CB10 1SA Cambridge, UK;(5) Institute of Biological Sciences, University of Wales, SY23 3DA Aberystwyth, UK;(6) 451 4184 MEBRF, University of Iowa, 52242 Iowa City, IA, USA

Abstract:	Background Tsetse flies transmit African trypanosomiasis leading to half a million cases annually. Trypanosomiasis in animals (nagana) remains a massive brake on African agricultural development. While trypanosome biology is widely studied, knowledge of tsetse flies is very limited, particularly at the molecular level. This is a serious impediment to investigations of tsetse-trypanosome interactions. We have undertaken an expressed sequence tag (EST) project on the adult tsetse midgut, the major organ system for establishment and early development of trypanosomes.

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