Compositional Correlations in the Chicken Genome |
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| Authors: | Héctor Musto Héctor Romero Alejandro Zavala Giorgio Bernardi |
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| Institution: | (1) Laboratorio de Organización y Evolución del Genoma, Sección Bioquímica, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay, UY;(2) Departamento de Genética, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay, UY;(3) Stazione Zoologica Anton Dohrn, Laboratorio di Evoluzione Molecolare, Villa Comunale, 80121 Napoli, Italy, IT |
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| Abstract: | This paper analyses the compositional correlations that hold in the chicken genome. Significant linear correlations were
found among the regions studied—coding sequences (and their first, second, and third codon positions), flanking regions (5′
and 3′), and introns—as is the case in the human genome. We found that these compositional correlations are not limited to
global GC levels but even extend to individual bases. Furthermore, an analysis of 1037 coding sequences has confirmed a correlation
among GC3, GC2, and GC1. The implications of these results are discussed.
Received: 9 December 1998 / Accepted: 18 April 1999 |
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| Keywords: | :Gallus gallus— Isochores — Genome organization — Genome evolution |
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