Terbutaline treatment inhibits the hCG-induced increase in venular permeability in the rat testis |
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Authors: | A Bergh J E Damber |
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Institution: | Department of Anatomy and Pathology, University of Ume?, Sweden. |
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Abstract: | Treatment with hCG results in an increase in venular permeability in the rat testis. This change in vascular permeability can be detected by the carbon-labelling technique, by measurement of the volume of interstitial fluid and by quantification of the leucocyte migration into the interstitial space. Carbon-labelling, interstitial fluid volume and leucocyte migration were all reduced in rats treated with hCG+ terbutaline compared to the values in animals given hCG only. However, terbutaline treatment did not influence the hCG-induced increase in testosterone secretion. These observations suggest that the hCG-induced increase in vascular permeability in the testis can be reduced by a beta-adrenergic agonist. |
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