The effect of CO on growth and product formation in batch cultures ofClostridium acetobutylicum |
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| Authors: | C. L. Meyer J. K. McLaughlin E. T. Papoutsakis |
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| Affiliation: | (1) Department of Chemical Engineering, Rice University, P.O. Box 1892, 77251 Houston, Texas, USA |
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| Abstract: | Summary Carbon monoxide sparged in batch fermentations ofC. acetobutylicum inhibits the production of H2 by the hydrogenase and enhances the production of solvents by making available larger amounts of NAD(P)H2 to the cells. CO also inhibits biomass growth and acid formation. Its effect is most pronounced under fermentation conditions of excess carbon- and nitrogen-source supply. |
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