Phylogenetic tree information aids supervised learning for predicting protein-protein interaction based on distance matrices |
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Authors: | Roger A Craig Li Liao |
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Institution: | (1) Department of Computer & Information Sciences, University of Delaware, Newark, DE 19716, USA |
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Abstract: | Background Protein-protein interactions are critical for cellular functions. Recently developed computational approaches for predicting
protein-protein interactions utilize co-evolutionary information of the interacting partners, e.g., correlations between distance
matrices, where each matrix stores the pairwise distances between a protein and its orthologs from a group of reference genomes. |
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Keywords: | |
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