Estimating genealogies from linked marker data: a Bayesian approach |
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Authors: | Dario Gasbarra Matti Pirinen Mikko J Sillanpää Elja Arjas |
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Institution: | (1) Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland;(2) National Public Health Institute (KTL), Helsinki, Finland |
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Abstract: | Background Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree
and of the gene flow therein. A few examples of such questions are haplotype estimation, relatedness and relationship estimation,
gene mapping by combining pedigree and linkage disequilibrium information, and estimation of population structure. |
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