Automated group assignment in large phylogenetic trees using GRUNT: GRouping,Ungrouping, Naming Tool |
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Authors: | Daniel Dalevi Todd Z DeSantis Jakob Fredslund Gary L Andersen Victor M Markowitz Philip Hugenholtz |
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Affiliation: | 1.Biological Data Management and Technology Center,Lawrence Berkeley National Laboratory,Berkeley,USA;2.Center for Environmental Biotechnology,Lawrence Berkeley National Laboratory,Berkeley,USA;3.Bioinformatics Research Center,University of Aerhus,?rhus C,Denmark;4.Microbial Ecology Program,DOE Joint Genome Institute,Walnut Creek,USA |
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Abstract: | Background Accurate taxonomy is best maintained if species are arranged as hierarchical groups in phylogenetic trees. This is especially important as trees grow larger as a consequence of a rapidly expanding sequence database. Hierarchical group names are typically manually assigned in trees, an approach that becomes unfeasible for very large topologies. |
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