| 缺氧与高渗溶液对家兔颈动脉体化学感受器活动的影响 |
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| 引用本文： | 王燕凌,庞雷.缺氧与高渗溶液对家兔颈动脉体化学感受器活动的影响[J].中国应用生理学杂志,1999,15(2):162-164. |
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| 作者姓名： | 王燕凌 庞雷 |
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| 作者单位： | 河北省医学科学院病理生理研究室 |
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| 摘 要： | 目的和方法：实验在游离灌流的颈动脉体窦神经标本上，观察氧分压降低和渗透压升高对化学感受性单位放电的影响。共记录７２个有自发放电的化学感受性单位对二者的反应。结果：仅对ＰＯ２降低有反应的化学感受性单位有２２例（占３０．６％），对两种自然刺激均有反应的化学感受性单位有３５例（占４８．６％），仅高渗引起化学感受性单位放电增加的有１５例（占２０．８％）。结论：在颈动脉体中不但存在着对缺氧敏感的化学感受性单位，还存在着对渗透压敏感的化学感受性单位，它们对氧分压、渗透压的改变有不同的敏感性。
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| 关 键 词： | 缺氧 高渗溶液 颈动脉体 化学感受器 传入单位放电 |
EFFECTS OF HYPOXIA AND HYPEROSMOTIC SOLUTION ON THE ACTIVITY OF THE RABBITS CAROTID CHEMORECEPTOR |
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| Wang yanling,Pang Lei,Miao Zhihui,Dong Li.EFFECTS OF HYPOXIA AND HYPEROSMOTIC SOLUTION ON THE ACTIVITY OF THE RABBITS CAROTID CHEMORECEPTOR[J].Chinese Journal of Applied Physiology,1999,15(2):162-164. |
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| Authors: | Wang yanling Pang Lei Miao Zhihui Dong Li |
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| Abstract: | Aim and Methods:The effects of hypoxia and hyperosmotic solution on the afferent unit discharge of rabbit carotid chemoreceptor were studied in the carotid body sinus nerve preparation. A total of 72 chemoreceptive units were recorded. Results: Of the 72 units, 22(30. 50%)showed chemosensory responses only to decrease of PO 2;35(48. 6%) to both stimulants(PO 2 decrease and osmo tic pressure increase),15(20. 8%) to the hyperosmotic solution. The carotid body may contain different kinds of chemorecepters respectively sensitive to PO 2 and osmotic pressure. |
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| Keywords: | hypoxia hyperosmotic solution carotid body chemoreceptor afferent unit discharge |
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