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A review of the ethnomedicinal uses,phytochemistry and pharmacology of the <Emphasis Type="Italic">Pleiocarpa</Emphasis> genus
Authors:Olubunmi A Omoyeni  Ahmed A Hussein  Emmanuel Iwuoha  Ivan R Green
Institution:1.Department of Chemistry,University of the Western Cape,Bellville,South Africa;2.Department of Chemistry and Polymer Science,University of Stellenbosch,Matieland,South Africa
Abstract:Pleiocarpa genus is a flowering plant from the Apocynaceae family which are rich sources of phytochemicals and have been reported to be useful in the treatment of gastrointestinal ailments, fever, malaria, pain, diabetes and cancer. The aim of this review is to present the past and current ethnomedicinal uses, phytochemistry and the pharmacology of Pleiocarpa genus which are underexploited as revealed through this review in order to enhance its potential source of phytochemical leads in medicine. Some pharmacological activities of these plants based on their acclaimed ethnomedicinal uses have been investigated by various researchers. The chemical profile of the genus is limited to alkaloids and triterpenoids, where indole alkaloids may be considered as important taxonomical markers.
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