Phytochemicals from fern species: potential for medicine applications |
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| Authors: | Hui Cao Tsun-Thai Chai Xin Wang Maria Flaviana B Morais-Braga Jing-Hua Yang Fai-Chu Wong Ruibing Wang Huankai Yao Jianguo Cao Laura Cornara Bruno Burlando Yitao Wang Jianbo Xiao Henrique D M Coutinho |
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| Institution: | 1.College of Food Science,Fujian Agriculture and Forestry University,Fuzhou,China;2.Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine,University of Macau,Taipa,Macau;3.Department of Chemical Science,Faculty of ScienceUniversiti Tunku Abdul Rahman,Kampar,Malaysia;4.Department of Biology,Shanghai Normal University,Shanghai,China;5.Laboratory of Microbiology and Molecular Biology,Regional University of Cariri–URCA,Crato,Brazil;6.Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology,Yunnan University,Kunming,China;7.Centre for Biodiversity Research,Universiti Tunku Abdul Rahman,Kampar,Malaysia;8.School of Pharmacy, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy,Xuzhou Medical University,Jiangsu,China;9.Faculty of Health Sciences,University of Macau,Taipa,Macau;10.Dipartimento di Scienze della Terra dell’Ambiente e della Vita, Polo Botanico,Università degli Studi di Genova,Genoa,Italy;11.Dipartimento di Scienze e Innovazione Tecnologica,Università del Piemonte Orientale “Amedeo Avogadro”,Alessandria,Italy;12.Istituto di Biofisica,Consiglio Nazionale delle Ricerche,Genoa,Italy |
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| Abstract: | Ferns are an important phytogenetic bridge between lower and higher plants. Historically they have been used in many ways by humans, including as ornamental plants, domestic utensils, foods, and in handicrafts. In addition, they have found uses as medicinal herbs. Ferns produce a wide array of secondary metabolites endowed with different bioactivities that could potentially be useful in the treatment of many diseases. However, there is currently relatively little information in the literature on the phytochemicals present in ferns and their pharmacological applications, and the most recent review of the literature on the occurrence, chemotaxonomy and physiological activity of fern secondary metabolites was published over 20 years ago, by Soeder (Bot Rev 51:442–536, 1985). Here, we provide an updated review of this field, covering recent findings concerning the bioactive phytochemicals and pharmacology of fern species. |
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