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Cadinane-type sesquiterpenoids from Schisandra bicolor
Affiliation:1. College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, PR China;2. School of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211, PR China;3. Department of Chemistry, University of Toronto, Toronto, M5S3H4, Canada
Abstract:The phytochemical investigation on the stems of Schisandra bicolor led to the isolation of seven cadinane-type sesquiterpenoids, 2-hydroxy-11,12-dehydrocalamenene (1), ent-T-muurolol (2), (+)-ent-epicubenol (3), (1S,4S)-7,8-dihydroxy-11,12-dehydrocalamenene (4), cadinane-T-cadinol (5), (−)-cadin-4,10(15)-dien-11-oic acid (6), and cadina-4,10(15)-dien-3-one (7). Their structures were determined by extensive analysis of their spectroscopic data. All the isolates were isolated from this species for the first time. The chemotaxonomic significance of these compounds was also summarized.
Keywords:Cadinane-type sesquiterpenoid  Chemotaxonomy
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