Diterpenoids from the South China Sea soft coral Sarcophyton solidum |
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| Institution: | 1. Doctoral Degree Program in Marine Biotechnology, National Sun Yat-sen University and Academia Sinica, Kaohsiung 804 Taiwan, ROC;2. National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan, ROC;3. Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan, ROC;4. Division of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 613, Taiwan, ROC;5. Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung 944, Taiwan, ROC;6. Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine and Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan, ROC;7. Research Center for Industry of Human Ecology and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan, ROC;8. Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan, ROC;9. Department of Biotechnology, Asia University, Taichung 413, Taiwan, ROC;10. Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan, ROC;11. School of Pharmacy, College of Pharmacy, China Medical University, Taichung 404, Taiwan, ROC;12. Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan, ROC;13. Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan, ROC;14. Center for Molecular Medicine, China Medical University Hospital, Taichung 404, Taiwan, ROC;1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555, Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China;2. University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China;3. Marine Biomedical Research Institute, Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical University, Zhanjiang 524023, China;4. Open Studio for Druggability Research of Marine Natural Products, Pilot National Laboratory for Marine Science and Technology (Qingdao), 1 Wenhai Road, Aoshanwei, Jimo, Qingdao 266237, China;5. Syngenta, Jealott’s Hill International Research Centre, Bracknell, Berkshire RG42 6EY, United Kingdom;1. State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People’s Republic of China;2. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People’s Republic of China;3. Shanghai Collaborative Innovation Center for Biomanufacturing Technology, 130 Meilong Road, Shanghai 200237, People’s Republic of China;4. Biology Department, College of Life and Environment Science, Shanghai Normal University,100 Guilin Road, Shanghai 200234, People’s Republic of China;5. College of Materials Science and Engineering, Central South University of Forestry and Technology, 498 South Shaoshan Road, Changsha 410004, People’s Republic of China;1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zuchongzhi Road 555 Zhangjiang Hi-Tech Park, Shanghai 201203, China;2. Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Via Campi Flegrei, 34, 80078 Pozzuoli, Naples, Italy |
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| Abstract: | Chemical investigation of the South China Sea soft coral Sarcophyton solidum has led to the isolation of one new (1) and seven known (2–8) diterpenoids, including three sarsolenanes (1–3), two capnosanes (4 and 5), and three cembranes (6–8). Sarsolilide B (4) was firstly con?rmed by single-crystal X-ray diffraction. Compounds 1, 3, 4, and 6–8 were isolated from S. solidum for the first time, and 1, 2, and 4–7 were considered as the chemotaxonomic markers for the species S. solidum. |
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| Keywords: | Sarsolenane Capnosane Cembrane |
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