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The proteomic landscape of genome-wide genetic perturbations
Institution:1. The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW1 1AT, UK;2. Precision Proteomics Center, Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, 7265 Davos, Switzerland;3. Charité Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany;4. Department of Biochemistry, Cambridge Centre for Proteomics, University of Cambridge, Cambridge CB2 1QW, UK;5. Charité Universitätsmedizin, Core Facility - High Throughput Mass Spectrometry, 10117 Berlin, Germany;6. Department of Molecular Genetics, University of Toronto, Toronto, ON M5S3E1, Canada;7. The Donnelly Centre, University of Toronto, Toronto, ON M5S3E1, Canada;8. RIKEN Center for Sustainable Resource Science, Wako, 351-0198 Saitama, Japan;9. Wellcome Centre for Cell Biology, University of Edinburgh, Max Born Crescent, Edinburgh EH9 3BF, Scotland, UK;10. The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK;11. Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
Abstract:
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  • Keywords:Saccharomyces cerevisiae  quantitative proteomics  data-independent acquisition  knockout  deletion  systems biology  functional proteomics  high throughput  functional genomics  gene annotation
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