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NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs
Affiliation:1. Department of Immunology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA;2. Animal Resources Center and the Veterinary Pathology Core, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA
Abstract:
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  • Keywords:NLRP12  heme  PAMP  DAMP  IRF1  hemolysis  inflammasome  inflammatory cell death  pyroptosis  apoptosis  necroptosis  caspase  gasdermin  TLR2  TLR4  caspase-8  caspase-1  RIPK3
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