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Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
Affiliation:1. Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, Wales CF14 4XN, UK;2. Systems Immunology Research Institute, Cardiff, Wales CF14 4XN, UK;3. Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, Wales CF14 4XN, UK;4. National Center for Cancer Immune Therapy, Department of Oncology, Copenhagen University Hospital, Herlev, Denmark;5. The Zeeman Institute, University of Warwick, Coventry CV4 7AL, UK
Abstract:
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  • Keywords:T cell receptor  TCR  tumor-infiltrating lymphocytes  TILs  TIL therapy  cancer immunotherapy  TCR-T  peptide-HLA  HLA class I
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