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Macrophage receptors implicated in the “adaptive” form of innate immunity |
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| Authors: | DME Bowdish MS Loffredo S Mukhopadhyay Alberto Mantovani S Gordon |
| Institution: | aSir William Dunn School of Pathology, University of Oxford, 10 South Parks Road, Oxford OX1 3RE, UK;bResearch Laboratory in Immunology and Inflammation, Istituto Clinico Humanitas Via Manzoni, 56, 20089 Rozzano, Milan, Italy |
| Abstract: | The adaptive component of innate immunity occurs during the course of infection when antigen presenting cells alter expression of soluble or surface associated pattern recognition receptors. This results in increased recognition of a broad spectrum of pathogens, enhancement of effector functions and altered regulation of the inflammatory response. |
| Keywords: | Macrophages Innate immunity Scavenger receptors Dectin-1 Pentraxin |
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