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Biochemical genetic markers in the Kadazans of Sabah,Malaysia
Authors:S G Tan  Y -S Teng  J Ganesan  K Y Lau  L E Lie-Injo
Institution:(1) Department of Biology, University Pertanian Malaysia, Serdang, Selangor, Malaysia;(2) University of California International Center for Medical Research, Kuala Lumpur, Malaysia;(3) Present address: Department of Human Biology, The John Curtin School of Medical Research, 2601 Canberra, ACT, Australia;(4) Institute for Medical Research, Kuala Lumpur, Malaysia;(5) University of California International Center for Medical Research, Kuala Lumpur, Malaysia;(6) Department of Epidemiology and International Health, University of California, San Francisco, California, U.S.A.;(7) University of California, 1699 HSW, 94143 San Francisco, CA, U.S.A.
Abstract:Summary Kadazans, the largest indigenous group in Sabah, northern Borneo, were surveyed for glyoxalase I, phosphoglucomutase I, red cell acid phosphatase, esterase D, adenosine deaminase, soluble glutamate pyruvate transaminase, soluble glutamate oxaloacetate transaminase, 6-phosphogluconate dehydrogenase, uridine monophosphate kinase, adenylate kinase, peptidase B and D, superoxide dismutase, C5, group specific component, haptoglobin and transferrin.Kadazans were found to be polymorphic for GLOI, PGMI, RCAP, esterase D, ADA, s-Gpt, 6PGD, UMPK, Gc, C5, haptoglobin and peptidase B. Rare variants were found for transferrin and peptidase D. No variant was found for s-Got, SOD and AK.
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