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Effect of the Diagnostic Criteria of the International Association of Diabetes and Pregnancy Study Groups on the Prevalence of Gestational Diabetes Mellitus In Urban Mexican Women: A Cross-Sectional Study
Institution:1. Department Of Endocrinology, Instituto Nacional De Perinatología Isidro Espinosa, De, Los Reyes, México City,;1. London School Hygiene and Tropical Medicine, Keppel St, Bloomsbury, London, WC1E 7HT, UK;2. Sociedad Mexicana de Salud Pública, Herschel 109, Col. Anzures, Miguel Hidalgo, C.P.11590, Mexico City, Mexico;3. Harvard Medical School, 641 Huntington Ave, Boston, MA 02115, USA;4. Institute for Global Health, University College London, Keppel St, Bloomsbury, London, WC1E 7HT, UK;5. Usher Institute, University of Edinburgh, Medical School, Teviot Place, Edinburgh EH8 9AG, UK
Abstract:ObjectiveTo explore the prevalence of gestational diabetes mellitus (GDM), defined by the previous criteria of the American Diabetes Association (ADA), as well as the criteria suggested by the International Association of Diabetes and Pregnancy Study Groups (IADPSG), in an unselected group of urban Mexican pregnant women and to analyze the frequency of large for gestational age (LGA) newborns in this same group of women with use of both diagnostic criteria.MethodsA cross-sectional study included 803 consecutive Mexican urban women with a singleton pregnancy, without concomitant diseases and no prior history of GDM, who underwent a 2-step screening protocol for diagnosis of GDM at admission to prenatal care.ResultsThe ADA criteria identified 83 women (10.3%) whereas the IADPSG criteria diagnosed 242 women (30.1%) having GDM (P = .0001). Fasting glucose concentrations during the 100-g 3-hour oral glucose tolerance test were abnormal in 116 women (14.4%) and in 160 women (19.9%) on the basis of ADA and IADPSG criteria, respectively (P = .004). The frequency of LGA newborns was 7.4% based on IADPSG criteria and 6.0% based on ADA criteria—no significant difference (P = .64).ConclusionWith use of the IADPSG criteria, the prevalence of GDM increased almost 3-fold in comparison with that for the ADA criteria. Nevertheless, no significant difference was found in the prevalence of LGA newborns. (Endocr Pract. 2012;18:146-151)
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