Escherichia coli mutants with a temperature-sensitive alcohol dehydrogenase. |
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Authors: | W Lorowitz and D Clark |
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Abstract: | Mutants of Escherichia coli resistant to allyl alcohol were selected. Such mutants were found to lack alcohol dehydrogenase. In addition, mutants with temperature-sensitive alcohol dehydrogenase activity were obtained. These mutations, designated adhE, are all located at the previously described adh regulatory locus. Most adhE mutants were also defective in acetaldehyde dehydrogenase activity. |
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