|
|||||
|
|
7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 inhibitors: a potential treatment for asthma |
|
| Authors: | Buckley George M Cooper Nicola Davenport Richard J Dyke Hazel J Galleway Fiona P Gowers Lewis Haughan Alan F Kendall Hannah J Lowe Christopher Montana John G Oxford Janet Peake Joanna C Picken C Louise Richard Marianna D Sabin Verity Sharpe Andrew Warneck Julie B H |
| Institution: | Celltech R & D, Granta Park, Great Abington, Cambridge CB1 6GS, UK. |
| Abstract: | The synthesis and pharmacological profile of a novel series of 7-methoxy-furo2,3-c]pyridine-4-carboxamides is described. Some of these compounds were found to be potent inhibitors of phosphodiesterase type 4 (PDE4). |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ | |