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Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein Expression
Authors:Yanfei Qi  Wei Wang  Jinbiao Chen  Lan Dai  Dominik Kaczorowski  Xin Gao  Pu Xia
Institution:From the Signal Transduction Program, Centenary Institute, University of Sydney, Sydney, NSW 2042, Australia and ;the §Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China
Abstract:
Keywords:endoplasmic reticulum stress (ER stress)  lipotoxicity  sphingolipid  sphingosine kinase (SphK)  unfolded protein response (UPR)  IRE1α    hepatocytes
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