Blood concentrations of the cytokines IL-1beta,IL-6, IL-10, TNF-alpha and IFN-gamma during experimentally induced swine dysentery |
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Authors: | Robert Kruse Birgitta Essén-Gustavsson Caroline Fossum Marianne Jensen-Waern |
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Affiliation: | (1) Department of Clinical Sciences, Section for Comparative Physiology and Medicine, Swedish University of Agricultural Sciences, P.O. Box 7054, S-750 07 Uppsala, Sweden;(2) Department of Molecular Biosciences, Section of Veterinary Immunology and Virology, Swedish University of Agricultural Sciences, P.O. Box 7054, S-750 07 Uppsala, Sweden |
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Abstract: | Background Knowledge of the cytokine response at infection with Brachyspira hyodysenteriae can help understanding disease mechanisme involved during swine dysentery. Since this knowledge is still limited the aim of the present study was to induce dysentery experimentally in pigs and to monitor the development of important immunoregulatory cytokines in blood collected at various stages of the disease. |
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