Identification of latent periodicity in domains of alkaline proteases |
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Authors: | Xiaofeng Ji Jun Sheng Fang Wang Suzhen Zhang Jianhua Hao Haiying Wang Mi Sun |
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Institution: | Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao, Shandong. |
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Abstract: | Internal repeats in protein sequences have wide-ranging implications for the structure and function of proteins. A keen analysis
of the repeats in protein sequences may help us to better understand the structural organization of proteins and their evolutionary
relations. In this paper, a mathematical method for searching for latent periodicity in protein sequences is developed. Using
this method, we identified simple sequence repeats in the alkaline proteases and found that the sequences could show the same
periodicity as their tertiary structures. This result may help us to reduce difficulties in the study of the relationship
between sequences and their structures. |
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