Pasteurella haemolytica is highly sensitive to ultraviolet irradiation |
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| Authors: | R Y Lo L E MacDonald |
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| Institution: | Department of Microbiology, University of Guelph, Ont., Canada. |
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| Abstract: | The response of Pasteurella haemolytica to ultraviolet irradiation was determined. The results for survival show that P. haemolytica is very sensitive to UV-irradiation. This UV-sensitivity is similar to E. coli strains defective in UV repair mechanism(s). Analysis of the distribution of TCA insoluble versus TCA soluble 3H]thymine dimers in UV-irradiated DNA of P. haemolytica during a 2-h post-irradiation period indicates that the bacterium is deficient in an excision-repair system. These data suggest that P. haemolytica lacks some of the important mechanisms to repair UV-induced damage. |
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