Involvement of antigen and I-J determinants in the induction of effector T suppressor cells by immune B cells |
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| Authors: | T Shimamura T Yoshida |
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| Affiliation: | Department of Microbiology, Tokai University School of Medicine, Isehara, Japan. |
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| Abstract: | Immune B cells induce effector T suppressor cells in vitro. The B cells act as antigen-presenting cells, and express both I-A and I-J determinants. Antigen and I-J determinants are required for the induction of suppressor T cells by immune B cells, but I-A determinants are not. These findings indicate that precursors of suppressor T cells appear to recognize antigen in the context of I-J determinants on the surface of immune B cells. |
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