Lectin-mediated agglutination of preimplantation mouse embryos |
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Authors: | Terry Magnuson Christopher W. Stackpole |
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Affiliation: | Memorial Sloan-Kettering Cancer Center, Walker Laboratory, Rye, NY 10580, USA |
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Abstract: | Plant lectins were used to monitor qualitative changes in carbohydrate-containing receptors during preimplantation mouse development. Beginning at the morula stage, an age-related decline was observed in agglutination of early mouse embryos by concanavalin A (ConA). In contrast, wheat germ agglutinin (WGA) and Ricinus communis agglutinin (RCA) agglutinated embryos strongly throughout preimplantation development. |
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