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Induction of the nuclear factor HIF-1alpha in acetaminophen toxicity: evidence for oxidative stress
Authors:James Laura P  Donahower Brian  Burke Angela S  McCullough Sandra  Hinson Jack A
Affiliation:a Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA
b Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR, USA
c Arkansas Children’s Hospital Research Institute, Little Rock, AR, USA
Abstract:
Keywords:Acetaminophen   Oxidative stress   Mitochondrial permeability transition   Hypoxia inducible factor   Hypoxia   Glutathione   Nitric oxide   Hepatotoxicity
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