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Association of serum markers with improvement in clinical response measures after treatment with golimumab in patients with active rheumatoid arthritis despite receiving methotrexate: results from the GO-FORWARD study
Authors:Sudha Visvanathan  Mahboob U Rahman  Edward Keystone  Mark Genovese  Lars Klareskog  Elizabeth Hsia  Michael Mack  Jacqui Buchanan  Michael Elashoff  Carrie Wagner
Affiliation:(1) Centocor Research and Development, Inc, 200 Great Valley Parkway, 19355 Malvern, PA, USA;(2) University of Pennsylvania School of Medicine, 3620 Hamilton Walk, 19104 Philadelphia, PA, USA;(3) University of Toronto, 27 King’s College Circle, M5 S 3G4 Toronto, ON, Canada;(4) Mount Sinai Hospital, 600 University Avenue Toronto, M5G 1X5, ON, Canada;(5) Stanford University, 450 Serra Mall, 94305 Palo Alto, CA, USA;(6) Karolinska Institute, Sweden and Karolinska Hospital, Huddinge, SE-171 77 Stockholm, 141 86 Stockholm, Sweden;(7) Johnson & Johnson Pharmaceutical Services, LLC, 200 Great Valley Parkway, 19355 Malvern, PA, USA;(8) Elashoff Consulting, 11124 Yellow Leaf Way, 20876 Germantown, MD, USA;(9) Hoffman La-Roche, 340 Kingsland Street, 07110 Nutley, NJ, USA;(10) Pfizer Inc, 500 Arcola Road, 19426 Collegeville, PA, USA;(11) Buchanan Biotech Consulting, PO Box 1326, 94042 Mountain View, CA, USA
Abstract:

Introduction  

The goal of this study was to identify serum markers that are modulated by treatment with golimumab with or without methotrexate (MTX) and are associated with clinical response.
Keywords:
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