Silicone-stimulated anthraquinone production and release by Morinda citrifolia in a two-liquid-phase system |
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Authors: | Lucilla Bassetti Joli Pijnenburg Johannes Tramper |
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Affiliation: | (1) Food and Bioprocess Engineering Group, Wageningen Agricultural University, P.O. Box 8129, 6700 Wageningen, EV, The Netherlands |
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Abstract: | Summary A 2.5-fold increase in the release of intracellular anthraquinones was obtained by adding 1 ml L-1 silicone A to suspension cultures of Morinda citrifolia. Cell growth and secondary metabolite production were not affected even at high silicone A concentrations. Performance of the silicone treatment in a two-liquid-phase system (5 ml n-hexadecane/50 ml medium) resulted in a 150% increase of the overall secondary metabolite productivity. |
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