Continuous suspended cell culture of Mentha piperita in cell-recycled air-lift bioreactor |
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| Authors: | I S Chung Y M Kang J H Oh T Kim H J Lee Y A Chae |
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| Institution: | (1) Department of Genetic Engineering, Kyung Hee University, 449-701 Suwon, Korea;(2) RCNBMA, Seoul National University, 441-744 Suwon, Korea |
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| Abstract: | Summary A cell-recycled air-lift bioreactor was studied for its performance in cultivation of Mentha piperita cells producing essential oils. The reactor system sustained a stable operation over 30 days with the aid of a cell settler. The maximum cell concentration reached 50% packed cell volume and it occurred at the dilution rate of 0.27 day-1. Volumetric productivity of essential oils in this system was substantially higher than that obtainable from batch culture. |
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